MHC antigen expression on bulk isolated macrophage-microglia from newborn mouse brain: induction of Ia antigen expression by γ-interferon
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MHC ANTIGEN INDUCTION BY INTERFERON y ON CULTURED MOUSE PANCREATIC
There is considerable interest concerning the pathological consequences of aberrant expression of HLA-DR (class II) MHC products on endocrine cells from patients with autoimmune diseases such as insulin-dependent diabetes mellitus (1) . The significance of MHC gene expression in pancreatic islet cells remains controversial (2). Normally, pancreatic (3 cells of mice constitutively express low le...
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The initiation of many antigen-specific, T-dependent immune responses requires the participation of accessory cells that express Ia antigens (1, 2). Recent evidence indicates that the Ia antigen expression of macrophages, a principle class of accessory cells, is regulated by lymphokines: Ste inman et al. (3) have reported that culture supernatants of Trypanosoma cruzi-activated spleen cells enh...
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The initiation of many antigen-specific, T-dependent immune responses requires the participation of accessory cells that express Ia antigens (1, 2). Recent evidence indicates that the Ia antigen expression of macrophages, a principle class of accessory cells, is regulated by lymphokines: Ste inman et al. (3) have reported that culture supernatants of Trypanosoma cruzi-activated spleen cells enh...
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ژورنال
عنوان ژورنال: Journal of Neuroimmunology
سال: 1987
ISSN: 0165-5728
DOI: 10.1016/0165-5728(87)90121-4